Abstract

Endemic goitre continues to be one of the most important health problems faced by developing countries, but epidemiological and aetiological information critical to health planning is lacking. This project will improve this situation by studying an endemic area of Liberia, Nimba county, to detemine the extent of the goitre problem, its aetiology, and its biochemical and environmental parameters. Findings of the study will facilitate the formulation of a health strategy to eradicate this disease.

Post-Project Summary

Researchers conducted epidemiological, metabolical, and nutritional surveys in Nimba County to determine the prevalence of endemic goitre. They also assessed common characteristics of Nimban thyroid function; determined urinary iodide and thiocyanate (SCN) levels; evaluated the link between diet and goitre; and assessed the relationship between water supply and the disease. The surveys revealed the existence of endemic zones, including one in which 54% of the population had the disease. It was also found that the total Nimba population had borderline euthyroid and hypothyroidism conditions. Researchers reported that low iodine levels caused goitre development; and that low levels were found in higher geological areas due to watershed composition. In terms of diet, it was concluded that a diet of cassava, gyba, and cola nut correlated with the prevalence of the disease. It was noted that project results provided the Liberian Ministry of Health with the data necessary for a goitre intervention program. The project leader presented project results at the international goitre meeting in Brussels.

Recipient Institution(s)